Tissue physiology and pathology of aromatase.

Stocco C. Tissue physiology and pathology of aromatase. Steroids. 2012 Jan;77(1-2):27-35. doi: 10.1016/j.steroids.2011.10.013. Epub 2011 Nov 13.

Abstract

Aromatase is expressed in multiple tissues, indicating a crucial role for locally produced oestrogens in the differentiation, regulation and normal function of several organs and processes. This review is an overview of the role of aromatase in different tissues under normal physiological conditions and its contribution to the development of some oestrogen-related pathologies.